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Integrins and Ion Channels: Molecular Complexes and Signaling (Advances in Experimental Medicine and Biology, 674) by Andrea Becchetti, Annarosa Arcangeli is a nonfiction available to read on EtoBox.

What is Integrins and Ion Channels: Molecular Complexes and Signaling (Advances in Experimental Medicine and Biology, 674) about?

Interdisciplinarity is more often invoked than practised. This is hardly surprising, considering the daunting vastness of modern biology. To reach a satisfactory understanding of a complex biological system, a wide spectrum of conceptual and experimental tools must be applied at different levels, from the molecular to the cellular, tissue and organismic. We believe the multifaceted regulatory interplay between integrin receptors and ion channels offers a rich and challenging field for researchers seeking broad biological perspectives. By mediating cell adhesion to the extracellular matrix, integrins regulate many developmental processes in the widest sense (from cell choice between differentiation and proliferation, to tissue remodeling and organogenesis). Rapidly growing evidence shows that frequent communication takes place between cell adhesion receptors and channel proteins. This may occur through formation of multiprotein membrane complexes that regulate ion fluxes as well as a variety of intracellular signaling pathways. In other cases, cross talk is more indirect and mediated by cellular messengers such as G proteins. These interactions are reciprocal, in that ion channel st

Who reads Integrins and Ion Channels: Molecular Complexes and Signaling (Advances in Experimental Medicine and Biology, 674)?

Author

Andrea Becchetti, Annarosa Arcangeli

Publisher

New York: Springer Science+Business Media ; Austin,Tex.: Landes Bioscience

Published

2010

Language

EN

ISBN

9781441960665

Category

nonfiction

Subjects

Medical, Science, Biology