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Evidence for Urea‐induced Hypometabolism in Isolated Organs of Dormant Ectotherms by Timothy J. Muir; Jon P. Costanzo; Richard E. Lee Jr is a Environmental Science article available to read on EtoBox.

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## Abstract Many organisms endure extended periods of dormancy by depressing their metabolism, which effectively prolongs the use of their endogenous energy stores. Though the mechanisms of hypometabolism are varied and incompletely understood, recent work suggests that urea accumulation in autumn and early winter contributes to reduced metabolism of hibernating wood frogs (__Rana sylvatica__). Urea accumulation during dormancy is a widespread phenomenon, and it has long been presumed that numerous species from diverse taxa benefit from its hypometabolic effect. To investigate the phylogenetic prevalence of urea‐induced hypometabolism, we studied four species of urea accumulators from the clades Amphibia (__Spea bombifrons__ and __Ambystoma tigrinum__), Reptilia (__Malaclemys terrapin__), and Gastropoda (__Anguispira alternata__), and one amphibian species (__R. pipiens__) that does not accumulate urea during dormancy. We measured rates of oxygen consumption (V̇O~2~) of excised organ samples from dormant animals in the presence or absence of physiological concentrations of urea. Three of the four urea‐accumulating species had at least one organ whose V̇O~2~ was significantly decrea

Who reads Evidence for Urea‐induced Hypometabolism in Isolated Organs of Dormant Ectotherms?

Author

Timothy J. Muir; Jon P. Costanzo; Richard E. Lee Jr

Publisher

Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1932-5223)

Published

2009

Language

EN

Field

Environmental Science (Life Sciences)