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The study investigates the role of GATA3 and epithelial-mesenchymal transition (EMT) markers in predicting long-term benefits from tamoxifen in postmenopausal patients with ER-positive breast cancer. High nuclear GATA3 expression correlates with lower rates of distant recurrence and greater long-term benefits from tamoxifen, while low GATA3 expression is linked to poor outcomes. The findings suggest that GATA3 and related markers could serve as important prognostic factors in managing ER-positive breast can

Author

benmessaouddouae

Language

EN