About this Medicine article

Conservative Surgical Approach for Thyroid and Lymph‐node Involvement in Papillary Thyroid Carcinoma of Childhood and Adolescence by Maura Massimino; Paola Collini; Silvia Fagundes Leite; Filippo Spreafico; Nicola Zucchini; Andrea Ferrari; Franco Mattavelli; Ettore Seregni; Maria Rita Castellani; Giulio Cantù; Franca Fossati‐Bellani; Juan Rosai is a Medicine article available to read on EtoBox.

## Abstract ## Background Prior to 1990s, papillary thyroid carcinomas (PTCs) in childhood/adolescence underwent a standard therapeutic approach (total thyroidectomy plus elective neck dissection, followed by radioactive iodine (RAI) ablation), with an overall survival of about 100%. The aim of this study is to outline the possibility of a conservative approach (hemithyroidectomy plus selective neck dissection of clinically involved nodes, followed by TSH‐suppressive therapy) in a selected group of patients. ## Procedure From 1968 to 2001, 42 pediatric PTC patients were treated at our institution. Absence of distant metastases and a tumor clinically limited to one lobe were both present in 28 cases that underwent a radical (20 cases) or a conservative (8 cases) surgical approach at the thyroid level. At cervical node level, 10 patients underwent a radical and 32 a conservative surgical approach. Clinicopathologic features at onset, type of therapy (radical vs. conservative), post‐operative complications, and outcome till May 31, 2004 were recorded. The impact of the type of surgery on outcome was evaluated. ## Results Overall and progression‐free survival (PFS) curves were found to

Author

Maura Massimino; Paola Collini; Silvia Fagundes Leite; Filippo Spreafico; Nicola Zucchini; Andrea Ferrari; Franco Mattavelli; Ettore Seregni; Maria Rita Castellani; Giulio Cantù; Franca Fossati‐Bellani; Juan Rosai

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1545-5009)

Published

2005

Language

EN

Field

Medicine (Health Sciences)