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Can I read Hypomagnesemia associated with chondrocalcinosis: A cross-sectional study on EtoBox?
Hypomagnesemia associated with chondrocalcinosis: A cross-sectional study by Pascal Richette; Ghazi Ayoub; Sophie Lahalle; Eric Vicaut; Abdul-Monem Badran; Francisca Joly; Bernard Messing; Thomas Bardin is a Medicine article available to read on EtoBox.
What is Hypomagnesemia associated with chondrocalcinosis: A cross-sectional study about?
## Abstract ## Objective To determine an association between magnesium (Mg) depletion and chondrocalcinosis, which has been reported but not investigated in a cross‐sectional study. ## Methods Prevalence of chondrocalcinosis was investigated in 144 individuals: 72 patients receiving home parenteral nutrition (HPN) compared with 72 age‐ and sex‐matched controls. Presence of chondrocalcinosis was assessed by knee radiographs. Blood serum and globular Mg levels and 24‐hour urinary Mg content were compared. ## Results Mean ± SD age for both patients and controls was 51 ± 17 years, and 51% in both groups were women. Mean duration of HPN was 6.4 years. Prevalence of chondrocalcinosis was markedly higher in patients receiving HPN than controls (16.6% versus 2.7%; __P__ = 0.006, odds ratio [OR] 7.0, 95% confidence interval [95% CI] 1.45–66.1). Mean ± SD serum and globular Mg levels were significantly lower in patients than controls (serum: 0.75 ± 0.09 mmoles/liter versus 0.81 ± 0.08 mmoles/liter, __P__ = 0.0006; globular Mg: 1.8 ± 0.31 mmoles/liter versus 2.0 ± 0.35 mmoles/liter, __P__ = 0.0003). Twenty‐four‐hour urinary Mg level was lower in patients than controls (mean ± SD 3.85 ± 1.50 m
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- Author
- Pascal Richette; Ghazi Ayoub; Sophie Lahalle; Eric Vicaut; Abdul-Monem Badran; Francisca Joly; Bernard Messing; Thomas Bardin
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0004-3591)
- Published
- 2007
- Language
- EN
- Field
- Medicine (Health Sciences)