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Treatment with exogenous leptin may affect weight loss in both lean and obese adults. A randomized, double-blind, placebo-controlled, multicenter, escalating dose cohort trial was conducted from April 1997 to October 1998. Subjects consumed a eucaloric diet to maintain body weight at the current value. Subjects were prescribed a diet that reduced their daily energy intake by 2100 kJ / d from the amount needed to maintain a stable weight

Author

Socrin

Language

EN