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Can I read Targeting Ferroptosis: a Novel Insight Against Myocardial Infarction and Ischemia–reperfusion Injuries on EtoBox?
Targeting Ferroptosis: a Novel Insight Against Myocardial Infarction and Ischemia–reperfusion Injuries by Xuejie Han; Jie Zhang; Jian Liu; Hongxia Wang; Fenghe Du; Xiangjun Zeng; Caixia Guo is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Targeting Ferroptosis: a Novel Insight Against Myocardial Infarction and Ischemia–reperfusion Injuries about?
Ferroptosis, a newly discovered form of regulated cell death dependent on iron and reactive oxygen species, is mainly characterized by mitochondrial shrinkage, increased density of bilayer membranes and the accumulation of lipid peroxidation, causing membrane lipid peroxidation and eventually cell death. Similar with the most forms of regulated cell death, ferroptosis also participated in the pathological metabolism of myocardial infarction and myocardial ischemia/reperfusion injuries, which are still the leading causes of death worldwide. Given the crucial roles ferroptosis played in cardiovascular diseases, such as myocardial infarction and myocardial ischemia/reperfusion injuries, it is considerable to delve into the molecular mechanisms of ferroptosis contributing to the progress of cardiovascular diseases, which might offer the potential role of ferroptosis as a targeted treatment for a wide range of cardiovascular diseases. This review systematically summarizes the process and regulatory metabolisms of ferroptosis, discusses the relationship between ferroptosis and myocardial infarction as well as myocardial ischemia/reperfusion injuries, which might potentially provide novel
Who reads Targeting Ferroptosis: a Novel Insight Against Myocardial Infarction and Ischemia–reperfusion Injuries?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Xuejie Han; Jie Zhang; Jian Liu; Hongxia Wang; Fenghe Du; Xiangjun Zeng; Caixia Guo
- Publisher
- Springer Science and Business Media LLC
- Published
- 2022
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)