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What is Histones Influence Monocyte Dynamics and Cytokines about?

This study investigates the impact of extracellular histones on monocyte distribution width (MDW) and cytokine release in blood cells, highlighting their role in hyperinflammation during sepsis and COVID-19. The results show that histones significantly increase MDW in a time- and dose-dependent manner, along with elevated levels of various inflammatory cytokines. These findings suggest that circulating histones may serve as potential biomarkers for predicting severe outcomes in patients with these condition

Author

tthnhu.biotech

Language

EN