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Effectiveness of ultrasonography and shear wave sonoelastography in Sjögren syndrome with salivary gland involvement by Yunus Emre Oruk; Mehmet Burak Çildağ; Can Zafer Karaman; Songül Çildağ is a Medicine article available to read on EtoBox.

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## Purpose This study investigated the effectiveness of major salivary gland ultrasonography (MSGUS) using a new grading system and shear wave elastography (SWE) in evaluating the major salivary glands of patients with Sjögren syndrome (SjS). ## Methods This prospectively-designed cross-sectional study included 49 SjS patients and 49 healthy controls. Major salivary glands were examined with gray-scale ultrasonography and SWE. A new grading system for salivary glands was developed using MSGUS findings. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of MSGUS and shear wave velocity (SWV) values were investigated. The MSGUS grading system and SWV values were evaluated together by logistic regression analysis. A cutoff value of SWE for salivary glands was determined. ## Results The sensitivity, specificity, PPV, and NPV of MSGUS were 69.4%, 73.5%, 72.3%, and 70.6% for the submandibular gland and 69.4%, 65.3%, 66.7%, and 68.1% for the parotid gland, respectively. The mean SWV values of the parotid and submandibular glands were significantly higher in SjS patients than in controls (P<0.05). The sensitivity, specificity, PPV, and NPV fo

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Author

Yunus Emre Oruk; Mehmet Burak Çildağ; Can Zafer Karaman; Songül Çildağ

Publisher

Korean Society of Ultrasound in Medicine

Published

2021

Language

EN

Field

Medicine (Health Sciences)