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The study investigates the compatibility of two new active pharmaceutical ingredients (APIs) with various excipients using non-thermal methods, specifically FT-IR and HPLC, under different storage conditions. Results indicate that FT-IR can detect incompatibilities more rapidly than HPLC, with significant structural changes observed in some excipients after only 3 days of isothermal stress testing. The findings suggest that FT-IR is a valuable tool for assessing drug-excipient interactions, potentially impa

Author

nanocigt

Language

EN