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Can I read Human papilloma virus (HPV) molecular diagnostics on EtoBox?
Human papilloma virus (HPV) molecular diagnostics by Christos Kroupis; Nikolaos Vourlidis is a Medicine article available to read on EtoBox.
What is Human papilloma virus (HPV) molecular diagnostics about?
Human Papilloma Virus (HPV) is becoming a menace worldwide, especially to the developing world, due to its involvement in a variety of malignancies, with cervical cancer being the most important and prevalent. There are many HPV types; HPV 16/18 are the most carcinogenic but few others are also characterized as high-risk (HR). They can cause a variety of low-or high-grade cellular abnormalities, most frequently detected in a routine Pap test. Most infections clear within 2 years, however, a minority persists and potentially could progress to cervical cancer. Molecular tests detecting HPV DNA, RNA or proteins are now being available either commercially or in-house developed. DNA detection is nowadays an established tool for diagnosis and monitoring of HPV-related disease, however, there is lack of a reference method and standardization with reference materials. The various available test formats create confusion on which molecular test to choose and what are its limitations. Therefore, the need for lab accreditation and participation in proficiency testing has to be stressed. Novel HPV biomarkers (RNA, protein etc.) are now intensively examined for their inclusion as adjunct tools.
Who reads Human papilloma virus (HPV) molecular diagnostics?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Christos Kroupis; Nikolaos Vourlidis
- Publisher
- Walter de Gruyter GmbH
- Published
- 2011
- Language
- EN
- Field
- Medicine (Health Sciences)