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The review discusses the Hippo pathway, a crucial signaling network regulating tissue growth and cell behavior in both Drosophila and mammals. It highlights the core components of the pathway, including the kinase cascade involving MST1/2 and LATS1/2, and their roles in phosphorylating transcriptional coactivators YAP and TAZ, which are essential for controlling gene expression related to cell proliferation and survival. Recent findings on the regulation of this pathway by various intrinsic and extrinsic si

Author

robloxwitharjun

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EN