Opening book details…
Can I read Synthesis and antibacterial activity of arylpiperazinyl oxazolidinones with diversification of the N-substituents on EtoBox?
Synthesis and antibacterial activity of arylpiperazinyl oxazolidinones with diversification of the N-substituents by Sun-Young Jang; Young Hwan Ha; Seung Whan Ko; Wonku Lee; Jongkook Lee; Sunghoon Kim; Yong Woo Kim; Won Koo Lee; Hyun-Joon Ha is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Synthesis and antibacterial activity of arylpiperazinyl oxazolidinones with diversification of the N-substituents about?
A series of 4-arylpiperazin-1-yl-3-phenyloxazolidin-2-one derivatives with diversification of the N-substituents such as methylene O-linked heterocycles, thioamide, dithiocarbamate, thiourea, and thiocarbamate were synthesized and evaluated as antibacterial agents. Their in vitro activities (MIC) were evaluated against MRSA and VRE resistant Gram-positive strains such as Staphylococcus and Enterococcus. Most of the compounds were more potent in vitro but less active in vivo than linezolid.
Who reads Synthesis and antibacterial activity of arylpiperazinyl oxazolidinones with diversification of the N-substituents?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Sun-Young Jang; Young Hwan Ha; Seung Whan Ko; Wonku Lee; Jongkook Lee; Sunghoon Kim; Yong Woo Kim; Won Koo Lee; Hyun-Joon Ha
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0960-894X)
- Published
- 2004
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)