Can I read Fluvoxamine Treatment in Veterans with Combat-related Post-traumatic Stress Disorder on EtoBox?

Fluvoxamine Treatment in Veterans with Combat-related Post-traumatic Stress Disorder by Rodrigo Escalona; Jose M. Canive; Lawrence A. Calais; Jonathan R.T. Davidson is a Psychology article available to read on EtoBox.

What is Fluvoxamine Treatment in Veterans with Combat-related Post-traumatic Stress Disorder about?

This study was designed to investigate the efficacy of the antidepressant fluvoxamine in the treatment of combat-related post-traumatic stress disorder (PTSD). Fifteen veterans with combat-related PTSD and no other psychiatric diagnosis except depression were recruited to participate in a 14-week openlabel study of fluvoxamine. Patients underwent a 30-day washout period and were rated with the Clinician Administered PTSD Scale (CAPS), Mississippi Scale, Beck Depression Inventory (BDI), Hamilton Rating Scale for Depression (HAM-D) and Hamilton Rating Scale for Anxiety (HAM-A) at baseline, and every 2 weeks until week 14. Three patients stopped fluvoxamine prematurely due to side effects and 7 withdrew consent before completing the 14week trial. Eight patients completed at least 8 weeks of treatment. The total daily dose of fluvoxamine ranged from 100 to 300 mg with a mean daily dose of 150 mg at week 14. Intent-to-treat analysis revealed a significant improvement in total CAPS scores, and in the intrusion and the avoidance/numbing subscales. The CAPS hyperarousal scores did not change significantly. HAM-A score also improved significantly. No significant changes were seen on the Mis

Who reads Fluvoxamine Treatment in Veterans with Combat-related Post-traumatic Stress Disorder?

Author

Rodrigo Escalona; Jose M. Canive; Lawrence A. Calais; Jonathan R.T. Davidson

Publisher

Hindawi Limited

Published

2002

Language

EN

Field

Psychology (Social Sciences)