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What is Indole Peptidomimetics as Antibacterials about?

This study reports the synthesis and biological evaluation of indole-based peptidomimetics as potential antibacterial agents against Gram-positive bacteria. Among the synthesized compounds, compound 28 exhibited significant antimicrobial activity, low toxicity, and stability, making it a promising candidate for treating infections caused by antibiotic-resistant bacteria. The research highlights the importance of hydrophobicity and cationic charge in enhancing the antibacterial efficacy of these peptidomimet

Author

Yuva Kishore

Language

EN