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EGF and IGF Receptors in Rat Mammary Gland Differentiation by Glenina is a document available to read on EtoBox.
1) The study examines the effect of ovariectomy and steroid replacement on receptors for epidermal growth factor (EGF) and insulin-like growth factors I and II (IGF-I, IGF-II) in mammary gland acini of rats. 2) Ovariectomy resulted in decreased EGF and IGF-I receptors and increased IGF-II receptors, without affecting ligand affinity. 3) While receptor concentrations are regulated by estradiol and progesterone, steroid replacement after ovariectomy showed receptor levels do not mediate the inhibito
- Author
- Glenina
- Language
- EN