About this Chemistry article
Synthesis and Antiproliferative Activities of Indolin-2-one Derivatives Bearing Amino Acid Moieties by Mathieu Sassatelli; Éric Debiton; Bettina Aboab; Michelle Prudhomme; Pascale Moreau is a Chemistry article available to read on EtoBox.
A convenient synthesis of indolin-2-ones substituted in the 3 position by an aminomethylene group bearing different amino acid moieties is described. Their antiproliferative activities were evaluated toward a panel of human solid tumor cell lines (PC 3, DLD-1, MCF-7, M4 Beu, A549, PA 1) and healthy cell lines (a murine fibroblast L929 and a human fibroblast primary culture).
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- Author
- Mathieu Sassatelli; Éric Debiton; Bettina Aboab; Michelle Prudhomme; Pascale Moreau
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0223-5234)
- Published
- 2006
- Language
- EN
- Field
- Chemistry (Physical Sciences)