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Abstracts of the 8th Meeting of the Italian Peripheral Nerve Study Group: 57 by D Cocito; A Chiò; G Isoardo; P Ciaramitaro; P Ghiglione; F Poglio; M Vercellino; R Mutani; B Bergamasco is a Medicine article available to read on EtoBox.

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BACKGROUND: Since 1991, five sets of electrophysiological criteria for CIDP have been reported. However, until now, receiver operator characteristic (ROC), such as sensitivity and specificity, of only AAN criteria were investigated, showing a high specificity, but intermediate sensitivity. The application of these criteria may be useful in clinical trials, but is inadequate in clinical practice, since they preclude immunomodulating treatment in patients who do not meet them. OBJECTIVE: 1) to evaluate the ROC and predictive value of five different electrophysiological criteria for CIDP (AAN, INCAT, Rotta et al, Nicholas et al. and Saperstein et al.); 2) to identify the most informative electrophysiological features indicative of demyelination by mean of the likelihood ratio; 3) to determine, in our series of cases, a set of minimal electrophysiological criteria (albeit aspecific) enough sensitive for CIDP diagnosis. PATIENTS AND METHODS: 20 patients with sensorimotor polyneuropathy, progressive for at least 2 months, with weakness in least two limbs and documented improvement in strength in response to immunotherapy. Other potential causes were excluded, including diabetes and IgM p

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Author

D Cocito; A Chiò; G Isoardo; P Ciaramitaro; P Ghiglione; F Poglio; M Vercellino; R Mutani; B Bergamasco

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 1085-9489)

Published

2003

Language

EN

Field

Medicine (Health Sciences)