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Trimethoprim is an antimetabolite antibiotic that disrupts bacterial folate synthesis, effective against a range of gram-positive and gram-negative bacteria, often used in combination with sulfamethoxazole (TMP/SMX) for various infections. It can be administered orally or intravenously, with indications including urinary tract infections, pneumonia, and MRSA. Common side effects include nausea and headache, while serious effects may involve kidney dysfunction and severe allergic reactions.

Author

zzana1679

Language

EN