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Prevalence and heart rate variability characteristics of premature ventricular contractions detected by 24-hour Holter among outpatients with palpitations in China: a cross-sectional study by Dong, Yan (author);Li, Xiaorong (author);Zheng, Wei (author);Man, Yilong (author);Liu, Jin (author);Yu, Ping (author);Zhang, Fengxiang (author);Yang, Bing (author);Cao, Kejiang (author) is a Medicine article available to read on EtoBox.
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## Objective To analyse the prevalence and heart rate variability (HRV) characteristics of premature ventricular contraction (PVC) detected by 24-hour Holter among Chinese outpatients with palpitations. ## Design A cross-sectional study. ## Setting This study was conducted in a tertiary hospital. ## Participants A total of 4754 outpatients who received 24-hour Holter for palpitations. ## Main outcome measures Prevalence, HRV time-domain and frequency-domain analyses of 24-hour Holter, and echocardiographic parameters were assessed. Propensity score matching (PSM) was applied to balance baseline variables (age, gender) to decrease the bias between comparison groups. ## Results The prevalence of PVC was 67.7% (3220/4754), and was higher in men than women (69.9% vs 66.0%, p=0.004); the prevalence of frequent PVCs (PVC burden≥5%) was 7.7% (368/4754). Older patients had the highest frequency of PVC among all patients. However, among 3220 patients with PVC, younger patients’ PVC burden was much higher. Matched 1:1 by age and gender, the HRV time-domain parameters in patients with PVC were all lower than those in patients without PVC (all p<0.05); for the HRV frequency-domain parameters,
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- Author
- Dong, Yan (author);Li, Xiaorong (author);Zheng, Wei (author);Man, Yilong (author);Liu, Jin (author);Yu, Ping (author);Zhang, Fengxiang (author);Yang, Bing (author);Cao, Kejiang (author)
- Publisher
- BMJ
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)