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Can I read [1,3]-Claisen Rearrangement via Removable Functional Group Mediated Radical Stabilization on EtoBox?
[1,3]-Claisen Rearrangement via Removable Functional Group Mediated Radical Stabilization by Md Nirshad Alam; Soumya Ranjan Dash; Anirban Mukherjee; Satish Pandole; Udaya Kiran Marelli; Kumar Vanka; Pradip Maity is a Chemistry article available to read on EtoBox.
What is [1,3]-Claisen Rearrangement via Removable Functional Group Mediated Radical Stabilization about?
A thermal O-to-C [1,3]-rearrangement of α-hydroxy acid derived enol ethers was achieved under mild conditions. The 2-aminothiophenol protection of carboxylic acids facilitates formation of the [1,3] precursor and its thermal rearrangement via stabilization of a radical intermediate. Experimental and theoretical evidence for dissociative radical pair formation, its captodative stability via aminothiophenol, and a unique solvent effect are presented. The aminothiophenol was deprotected from rearrangement products as well as after derivatization to useful synthons.
Who reads [1,3]-Claisen Rearrangement via Removable Functional Group Mediated Radical Stabilization?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Md Nirshad Alam; Soumya Ranjan Dash; Anirban Mukherjee; Satish Pandole; Udaya Kiran Marelli; Kumar Vanka; Pradip Maity
- Publisher
- American Chemical Society (ACS)
- Published
- 2021
- Language
- EN
- Field
- Chemistry (Physical Sciences)