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Clinical Outcomes of Patients Receiving Integrated PET/CT-Guided Radiotherapy for Head and Neck Carcinoma by Matthew R. Vernon; Mohit Maheshwari; Christopher J. Schultz; Michelle A. Michel; Stuart J. Wong; Bruce H. Campbell; Becky L. Massey; J. Frank Wilson; Dian Wang is a Medicine article available to read on EtoBox.

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## Purpose: We previously reported the advantages of (18)f-fluorodeoxyglucose-positron emission tomography (pet) fused with ct for radiotherapy planning over ct alone in head and neck carcinoma (hnc). the purpose of this study was to evaluate clinical outcomes and the predictive value of pet for patients receiving pet/ct-guided definitive radiotherapy with or without chemotherapy. ## Methods and materials: From december 2002 to august 2006, 42 patients received pet/ct imaging as part of staging and radiotherapy planning. clinical outcomes including locoregional recurrence, distant metastasis, death, and treatment-related toxicities were collected retrospectively and analyzed for disease-free and overall survival and cumulative incidence of recurrence. ## Results: Median follow-up from initiation of treatment was 32 months. overall survival and disease-free survival were 82.8% and 71.0%, respectively, at 2 years, and 74.1% and 66.9% at 3 years. of the 42 patients, seven recurrences were identified (three lr, one dm, three both lr and dm). mean time to recurrence was 9.4 months. cumulative risk of recurrence was 18.7%. the maximum standard uptake volume (suv) of primary tumor, adenop

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Author

Matthew R. Vernon; Mohit Maheshwari; Christopher J. Schultz; Michelle A. Michel; Stuart J. Wong; Bruce H. Campbell; Becky L. Massey; J. Frank Wilson; Dian Wang

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2008

Language

EN

Field

Medicine (Health Sciences)