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Association between fatality rate of COVID-19 and selenium deficiency in China by Zhang, Hai-Yang (author);Zhang, An-Ran (author);Lu, Qing-Bin (author);Zhang, Xiao-Ai (author);Zhang, Zhi-Jie (author);Guan, Xiu-Gang (author);Che, Tian-Le (author);Yang, Yang (author);Li, Hao (author);Liu, Wei (author);Fang, Li-Qun (author) is a Medicine article available to read on EtoBox.

What is Association between fatality rate of COVID-19 and selenium deficiency in China about?

## Background COVID-19 has impacted populations around the world, with the fatality rate varying dramatically across countries. Selenium, as one of the important micronutrients implicated in viral infections, was suggested to play roles. ## Methods An ecological study was performed to assess the association between the COVID-19 related fatality and the selenium content both from crops and topsoil, in China. ## Results Totally, 14,045 COVID-19 cases were reported from 147 cities during 8 December 2019–13 December 2020 were included. Based on selenium content in crops, the case fatality rates (CFRs) gradually increased from 1.17% in non-selenium-deficient areas, to 1.28% in moderate-selenium-deficient areas, and further to 3.16% in severe-selenium-deficient areas (__P__ = 0.002). Based on selenium content in topsoil, the CFRs gradually increased from 0.76% in non-selenium-deficient areas, to 1.70% in moderate-selenium-deficient areas, and further to 1.85% in severe-selenium-deficient areas (__P__ < 0.001). The zero-inflated negative binomial regression model showed a significantly higher fatality risk in cities with severe-selenium-deficient selenium content in crops than non-seleniu

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Author
Zhang, Hai-Yang (author);Zhang, An-Ran (author);Lu, Qing-Bin (author);Zhang, Xiao-Ai (author);Zhang, Zhi-Jie (author);Guan, Xiu-Gang (author);Che, Tian-Le (author);Yang, Yang (author);Li, Hao (author);Liu, Wei (author);Fang, Li-Qun (author)
Publisher
Springer Science and Business Media LLC
Published
2021
Language
EN
Field
Medicine (Health Sciences)

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