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This study evaluates the performance of a fully automated chemiluminescence immunoassay (CLIA) against the conventional enzyme-linked immunosorbent assay (ELISA) for detecting islet autoantibodies in type 1 diabetes (T1D). The results indicate that CLIA demonstrates good precision and high correlation with ELISA, although it underestimates certain antibody levels while overestimating others. The findings support the use of CLIA in large-scale screening programs for T1D, while emphasizing the need for improv

Author

Zakia Aszahrah

Language

EN