Can I read A practical synthesis of fibrinogen receptor antagonist MK-383. selective functionalization of (S)-tyrosine on EtoBox?

A practical synthesis of fibrinogen receptor antagonist MK-383. selective functionalization of (S)-tyrosine by John Y.L. Chung; Dalian Zhao; David L. Hughes; Edward J.J. Grabowski is a Chemistry article available to read on EtoBox.

What is A practical synthesis of fibrinogen receptor antagonist MK-383. selective functionalization of (S)-tyrosine about?

Abrtruct: A nractical4-stew smthesis of fibfinonen fece~tm maxmist MK-383. N-(n-butanesulfonyl)-O-(4-(4-pip&iuyl)-b;tyl)-(S)-tyn&e,-is accemplished 648% o&all yiel? from (S)-tyrosim: Hi~htiSlns in&tie: (i) &e dualuseof4-picolineasamashdformofpiperidine~andaaucleophile~ fura3-ca&ubmnoloSationwttll 3-tnum~l-chl~: (2) the use of trimethylsilyl groups for teqorwy protectioo of phenottc and carboxylate oxySens of (S)-tpusine that eatable selective N-sulfcnytatioa to be

Who reads A practical synthesis of fibrinogen receptor antagonist MK-383. selective functionalization of (S)-tyrosine?

Author

John Y.L. Chung; Dalian Zhao; David L. Hughes; Edward J.J. Grabowski

Publisher

Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0040-4020)

Published

1993

Language

EN

Field

Chemistry (Physical Sciences)