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Can I read Loss of Heterozygosity on Chromosome Arm 3P in Nasopharyngeal Carcinoma on EtoBox?
Loss of Heterozygosity on Chromosome Arm 3P in Nasopharyngeal Carcinoma by Li-Fu Hu; Gudny Eiriksdottir; Tatyana Lebedeva; Irina Kholodniouk; Andrei Alimov; Fu Chen; Yan Luo; Eugene R. Zabarovsky; Sigurdur Ingvarsson; George Klein; Ingemar Ernberg is a Medicine article available to read on EtoBox.
What is Loss of Heterozygosity on Chromosome Arm 3P in Nasopharyngeal Carcinoma about?
We have examined I 7 primary undifferentiated nasopharyngeal carcinoma biopsies for allelic loss on 3p, comparing the findings in tumors with those in normal lymphocyte D N A from the same patients. Ten polymorphic microsatellite markers were used between 3p I 3 and 3p26. Allelic IOU was observed in I 2 samples (70%). Two loci were most frequently affected D3S I067 (3p2 I . I -14.3) in 60% and D3S I 2 I 7 (3p 14.2-14. I ) in 58%. One tumor seemed to have a homozygous deletion at 3p26, detected by the D3S I297 marker. Analysis of the clinical data showed that an increased number of aberrations in 3p was correlated with more advanced tumor stages. Genes Chromosom Cancer 17:118-126 (1996).
Who reads Loss of Heterozygosity on Chromosome Arm 3P in Nasopharyngeal Carcinoma?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Li-Fu Hu; Gudny Eiriksdottir; Tatyana Lebedeva; Irina Kholodniouk; Andrei Alimov; Fu Chen; Yan Luo; Eugene R. Zabarovsky; Sigurdur Ingvarsson; George Klein; Ingemar Ernberg
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); Wiley-Liss Inc; Wiley (ISSN 1045-2257)
- Published
- 1996
- Language
- EN
- Field
- Medicine (Life Sciences)