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Can I read Myoclonus or tremor in orthostatism: An under-recognized cause of unsteadiness in Parkinson's disease on EtoBox?

Myoclonus or tremor in orthostatism: An under-recognized cause of unsteadiness in Parkinson's disease by Smaranda Leu-Semenescu; Emmanuel Roze; Marie Vidailhet; André-Pierre Legrand; Jean-Marc Trocello; Valérie Cochen; Sophie Sangla; Emmanuelle Apartis is a Medicine article available to read on EtoBox.

What is Myoclonus or tremor in orthostatism: An under-recognized cause of unsteadiness in Parkinson's disease about?

## Abstract Patients with Parkinson's disease (PD) often complain of unsteadiness. This can occur as the result of various neurological dysfunctions, including changes in postural adjustments, loss of postural reflexes, axial akinesia and rigidity, freezing and/or postural hypotension. In some cases these symptoms remain unexplained, and rare cases of unsteadiness have been attributed to tremor on standing. To delineate this condition, we investigated 11 consecutive PD patients with unexplained unsteadiness because of tremor on standing, seen in our department over a 6‐year period. All the patients had detailed clinical and electrophysiological investigations based on surface polygraphic electromyographic recordings. Four patients had fast orthostatic tremor (13–18 Hz), one had intermediate orthostatic tremor (8–9 Hz), and three had slow orthostatic tremor (4–6 Hz). The remaining 3 patients had orthostatic myoclonus, a condition that has not previously been reported in PD. Patients with fast tremor improved on clonazepam. Patients with slow tremor and myoclonus improved on levodopa and sometimes benefited further when clonazepam was added. These observations show the usefulness of

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Author
Smaranda Leu-Semenescu; Emmanuel Roze; Marie Vidailhet; André-Pierre Legrand; Jean-Marc Trocello; Valérie Cochen; Sophie Sangla; Emmanuelle Apartis
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0885-3185)
Published
2007
Language
EN
Field
Medicine (Health Sciences)

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