Can I read Total Synthesis of Taxol C and D Rings on EtoBox?
Total Synthesis of Taxol C and D Rings by anon_725382424 is a document available to read on EtoBox.
What is Total Synthesis of Taxol C and D Rings about?
The document summarizes the total synthesis of the chemotherapy drug Taxol through the completion of the C and D rings. Key steps include: 1) Cyclization of lactone 4 to form the enol ester 6 in 93% yield. 2) Decarbomethoxylation of 6 and temporary protection to provide compound 8, which was then converted to the diol carbonate 11 for structure confirmation. 3) Introduction of the oxetane D ring through multiple oxidation, addition, elimination, and protection steps starting from compound 8 to ultimatel
- Author
- anon_725382424
- Language
- EN