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Automated 4D analysis of dendritic spine morphology: applications to stimulus-induced spine remodeling and pharmacological rescue in a disease model by Sharon A Swanger; Xiaodi Yao; Christina Gross; Gary J Bassell is a Neuroscience article available to read on EtoBox.
What is Automated 4D analysis of dendritic spine morphology: applications to stimulus-induced spine remodeling and pharmacological rescue in a disease model about?
Uncovering the mechanisms that regulate dendritic spine morphology has been limited, in part, by the lack of efficient and unbiased methods for analyzing spines. Here, we describe an automated 3D spine morphometry method and its application to spine remodeling in live neurons and spine abnormalities in a disease model. We anticipate that this approach will advance studies of synapse structure and function in brain development, plasticity, and disease.
Who reads Automated 4D analysis of dendritic spine morphology: applications to stimulus-induced spine remodeling and pharmacological rescue in a disease model?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- Sharon A Swanger; Xiaodi Yao; Christina Gross; Gary J Bassell
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, [2008]-; Springer Science and Business Media LLC (ISSN 1756-6606)
- Published
- 2011
- Language
- EN
- Field
- Neuroscience (Life Sciences)