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Can I read Liquid Chromatographic–fluorimetric Method for the Estimation of Nitric Oxide Biosynthesis in the Central Nervous System on EtoBox?
Liquid Chromatographic–fluorimetric Method for the Estimation of Nitric Oxide Biosynthesis in the Central Nervous System by Iván Pérez-Neri; Sergio Montes; Marie-Catherine Boll; Jesús Ramı́rez-Bermúdez; Camilo Rı́os is a Chemistry article available to read on EtoBox.
What is Liquid Chromatographic–fluorimetric Method for the Estimation of Nitric Oxide Biosynthesis in the Central Nervous System about?
Some amino acids are involved in the biosynthesis of nitric oxide (NO), which has a physiological and pathophysiological role. To study NO biosynthesis, we compared arginine and citrulline levels in the cerebrospinal fluid (CSF) from patients with infectious and/or inflammatory processes within the central nervous system (CNS), with those from patients without those disorders. Arginine concentration was not significantly different between the groups (P = 0.115), whereas citrulline was significantly elevated in the first group (P = 0.020). We propose a simple chromatographic method to estimate NO biosynthesis ex vivo within the CNS, that may be applicable for the study of neurodegenerative and psychiatric diseases such as Parkinson's disease and schizophrenia.
Who reads Liquid Chromatographic–fluorimetric Method for the Estimation of Nitric Oxide Biosynthesis in the Central Nervous System?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Iván Pérez-Neri; Sergio Montes; Marie-Catherine Boll; Jesús Ramı́rez-Bermúdez; Camilo Rı́os
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 1873-376X)
- Published
- 2004
- Language
- EN
- Field
- Chemistry (Physical Sciences)