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Understanding Hybridoma Technology by brian.keli007 is a document available to read on EtoBox.
Hybridoma technology involves fusing antibody-producing B cells with myeloma cells to create hybridomas that produce monoclonal antibodies. This process, developed by César Milstein and Georges J. F. Köhler in 1975, has numerous applications in disease prevention, diagnosis, and treatment, particularly in identifying cell types and cancer markers. Monoclonal antibodies enhance diagnostic histopathology by improving the detection of tumors and metastases through specific immuno-cytochemical analysis.
- Author
- brian.keli007
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- EN