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Significant Loss of Skeletal Muscle Mass Occurs After Femoral Fragility Fracture by Aspen Miller; John Davison; Lisa Reider; Jason Wilken; Natalie Glass; Tessa Kirkpatrick; Cindy Headlee; Daniel Fitzpatrick; Erin Owen; J Lawrence Marsh; Michael Willey; Ruth Grossmann is a scholarly article available to read on EtoBox.

What is Significant Loss of Skeletal Muscle Mass Occurs After Femoral Fragility Fracture about?

## Abstract ## Objectives Femoral fragility fractures in the elderly result in devastating loss of physical function and muscle mass, which is a direct result of immobilization and nutrient deficiencies during healing. A better understanding of how muscle mass responds to injury is needed to critically evaluate nutrition interventions designed to prevent muscle loss and optimize function. The purpose of this study was to document sarcopenia, nutrition status, and changes in muscle mass after femoral fragility fractures. ## Methods A two-center prospective observational study enrolled individuals ≥65 years old admitted for operative fixation of a low-energy femoral fracture. Body composition was assessed within 72 hours of admission using bioelectrical impedance and repeated 6 and 12 weeks after injury. Sarcopenia was defined by gender-specific cutoffs for appendicular skeletal muscle mass index. Malnutrition was defined by Mini Nutritional Assessment®. Wilcoxon Signed Rank test was used to assess 6 and 12-week change from baseline in skeletal muscle mass (SMM). Wilcoxon Rank Sum test was used to compare the change in SMM in those with vs without malnutrition and sarcopenia. SMM res

Author

Aspen Miller; John Davison; Lisa Reider; Jason Wilken; Natalie Glass; Tessa Kirkpatrick; Cindy Headlee; Daniel Fitzpatrick; Erin Owen; J Lawrence Marsh; Michael Willey; Ruth Grossmann

Publisher

Elsevier BV

Published

2022

Language

EN