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Synthesis and Antifungal Activity of Camphoric Acid-based Acylhydrazone Compounds by Xian-Li Ma; Fang-Yao Li; Wen-Gui Duan; Jing-Ni Liao; Zhi-duo Lin; Gui-Shan Lin; Bo Cen; Fu-Hou Lei is a Engineering article available to read on EtoBox.
What is Synthesis and Antifungal Activity of Camphoric Acid-based Acylhydrazone Compounds about?
## Abstract In the search of novel potent bioactive compounds, 18 novel camphoric acid-based acylhydrazone compounds 4a–4r were designed and synthesized by the condensation reaction of __N__-amino camphorimide (3) with substituted benzaldehyde based on camphoric acid as the starting material. The target compounds were characterized by means of Fourier transform infrared (FTIR), ^1^H nuclear magnetic resonance (NMR), ^13^C NMR, electrospray ionization-mass spectrometry (ESI-MS), and elemental analysis. The preliminary bioassay showed that the following camphoric acid-based compounds exhibited excellent antifungal activity with an inhibition ratio of 95% against __Physalospora piricola__ at the concentration of 50 μg ml^-1^: __o__-bromophenyl acylhydrazone (4f), __p__-bromophenyl acylhydrazone (4g), __p__-methoxyphenyl acylhydrazone (4m), and __p__-hydroxyphenyl acylhydrazone (4p).
Who reads Synthesis and Antifungal Activity of Camphoric Acid-based Acylhydrazone Compounds?
It is typically read by researchers, students, and practitioners in Engineering.
- Author
- Xian-Li Ma; Fang-Yao Li; Wen-Gui Duan; Jing-Ni Liao; Zhi-duo Lin; Gui-Shan Lin; Bo Cen; Fu-Hou Lei
- Publisher
- Walter de Gruyter GmbH
- Published
- 2014
- Language
- EN
- Field
- Engineering (Physical Sciences)