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Preparation and spectroscopic properties of bioactive 1, 2, 3-triazole-linked boronate esters for use in antioxidant, antimicrobial, and DNA binding studies by Ahmet Kilic; Anas Alshhab; Veysi Okumus is a Chemistry article available to read on EtoBox.
What is Preparation and spectroscopic properties of bioactive 1, 2, 3-triazole-linked boronate esters for use in antioxidant, antimicrobial, and DNA binding studies about?
In this article, the preparation, spectral evaluation, and biological studies of bioactive 1, 2, 3-triazole-linked boronate esters are reported. The bioactive 1, 2, 3-triazole group linked-boronate esters have been designed and obtained by azido-functionalized boronate ester with different alkyne molecules via click chemistry approach under mild conditions. The prepared boronate esters (B1-5) were characterized using NMR (1H, 13C, and 11B) spectra, FT-IR spectra, UV-Vis spectra, LC-MS/MS spectra, elemental analysis, and melting point measurement techniques. After all structures of synthesized boronate esters were characterized in detail, the antimicrobial (antioxidant and antibacterial) and DNA binding properties of newly prepared boronate esters were investigated. The bioactive 1, 2, 3-triazole-linked boronate ester (B5) showed the highest radical scavenging (71.59 ± 1.85%) and reducing power activity (0.476 ± 0.01) at 200.0 μg/mL concentration. According to the method of reducing power activity, the compound (B5) exhibited the strongest activity with 0.476 ± 0.014. The anti-bacterial activity of all boronate esters (B1-5) was determined with four pathogenic bacteria. It was deter
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It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Ahmet Kilic; Anas Alshhab; Veysi Okumus
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Chemistry (Physical Sciences)