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This study investigates the protective effects of proton pump inhibitors (PPIs) against gastric antral ulcers induced by NSAIDs in mice, highlighting the role of capsaicin-sensitive afferent nerves (CSANs). The results indicate that PPIs, particularly lansoprazole, significantly inhibit ulcer formation, and that the protective effects are mediated through the activation of CSANs. Additionally, the study demonstrates that H2-receptor antagonists do not provide the same protective effect as PPIs in this conte

Author

hoangvinh429a1

Language

EN