Opening book details…
Can I read 2005 Probst Nat Immunol on EtoBox?
2005 Probst Nat Immunol by Priscila Freitas is a document available to read on EtoBox.
What is 2005 Probst Nat Immunol about?
The document discusses how resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4. It found that peripheral CD8+ T cell tolerance induced by resting dendritic cells depends on signaling via the costimulatory molecules PD-1 and CTLA-4. Blocking either of these molecules impaired tolerance induction, suggesting they act synergistically in maintaining peripheral tolerance.
- Author
- Priscila Freitas
- Language
- EN