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Lung Cancer CT Screening and Lung-RADS in a Tuberculosis-endemic Country: The Korean Lung Cancer Screening Project (K-LUCAS) by Hyungjin Kim; Hyae Young Kim; Jin Mo Goo; Yeol Kim is a Medicine article available to read on EtoBox.

What is Lung Cancer CT Screening and Lung-RADS in a Tuberculosis-endemic Country: The Korean Lung Cancer Screening Project (K-LUCAS) about?

Background Low-dose CT screening for lung cancer in a tuberculosis-endemic country may be less effective because of false-positive results caused by tuberculosis sequelae. Purpose To evaluate the impact of tuberculosis sequelae at CT screening according to the American College of Radiology Lung CT Screening Reporting and Data System (Lung-RADS) using data from the Korean Lung Cancer Screening Project (K-LUCAS). Materials and Methods This is a secondary analysis of K-LUCAS (ClinicalTrials.gov identifier NCT03394703), a nationwide Asian population-based, multicenter, prospective cohort study. Participants at high risk for lung cancer were enrolled between April 2017 and December 2018. Associations of tuberculosis sequelae with a positive screening result for lung cancer (defined as Lung-RADS categories 3 or 4) and diagnosis of lung cancer were analyzed with multivariable logistic regression. The diagnostic performance of Lung-RADS in predicting lung cancer was compared between participants with and participants without tuberculosis sequelae by using the χ test. Results A total of 11 394 participants (median age, 62 years; interquartile range, 58-67 years; 11 098 men) were evaluated.

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Author

Hyungjin Kim; Hyae Young Kim; Jin Mo Goo; Yeol Kim

Publisher

The Radiological Society of North America; Radiological Society of North America; Radiological Society of North America (RSNA) (ISSN 0033-8419)

Published

2020

Language

EN

Field

Medicine (Health Sciences)