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Brainstem primitive neuroectodermal tumors (bstPNET): Results of treatment with intensive induction chemotherapy followed by consolidative chemotherapy with autologous hematopoietic cell rescue by Jason R. Fangusaro; Rima F. Jubran; Jeffrey Allen; Sharon Gardner; Ira J. Dunkel; Mark Rosenblum; Mark P. Atlas; Ignacio Gonzalez-Gomez; Douglas Miller; Jonathan L. Finlay is a Medicine article available to read on EtoBox.

What is Brainstem primitive neuroectodermal tumors (bstPNET): Results of treatment with intensive induction chemotherapy followed by consolidative chemotherapy with autologous hematopoietic cell rescue about?

## Abstract We have evaluated the response rate and survival utilizing intensified chemotherapy followed by myeloablative chemotherapy with autologous hematopoietic cell rescue (AuHCR) and adjuvant radiation therapy in six young children with newly diagnosed brainstem primitive neuroectodermal tumors (bstPNET). Following maximum surgical resection of the tumor, patients received high dose induction chemotherapy including vincristine, cisplatin, cyclophosphamide, and etoposide. Eligible patients received a single cycle of myeloablative chemotherapy followed by AuHCR. Two patients survive at least 32 months with stable disease. This approach provides an alternative for young patients with bstPNET who in prior reports have had a uniformly fatal prognosis. Pediatr Blood Cancer 2008;50:715–717. © 2006 Wiley‐Liss, Inc.

Who reads Brainstem primitive neuroectodermal tumors (bstPNET): Results of treatment with intensive induction chemotherapy followed by consolidative chemotherapy with autologous hematopoietic cell rescue?

Author

Jason R. Fangusaro; Rima F. Jubran; Jeffrey Allen; Sharon Gardner; Ira J. Dunkel; Mark Rosenblum; Mark P. Atlas; Ignacio Gonzalez-Gomez; Douglas Miller; Jonathan L. Finlay

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1545-5009)

Published

2008

Language

EN

Field

Medicine (Health Sciences)