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Maternal exposure to airborne polychlorinated biphenyls (PCBs) and risk of adverse birth outcomes by Ane Bungum Kofoed; Laura Deen; Karin Sørig Hougaard; Kajsa Ugelvig Petersen; Harald William Meyer; Ellen Bøtker Pedersen; Niels Erik Ebbehøj; Berit Lilienthal Heitmann; Jens Peter Bonde; Sandra Søgaard Tøttenborg is a Medicine article available to read on EtoBox.

What is Maternal exposure to airborne polychlorinated biphenyls (PCBs) and risk of adverse birth outcomes about?

Human health effects of airborne lower-chlorinated polychlorinated biphenyls (LC-PCBs) are largely unexplored. Since PCBs may cross the placenta, maternal exposure could potentially have negative consequences for fetal development. We aimed to determine if exposure to airborne PCB during pregnancy was associated with adverse birth outcomes. In this cohort study, exposed women had lived in PCB contaminated apartments at least one year during the 3.6 years before conception or the entire first trimester of pregnancy. The women and their children were followed for birth outcomes in Danish health registers. Logistic regression was performed to estimate odds ratios (OR) for changes in secondary sex ratio, preterm birth, major congenital malformations, cryptorchidism, and being born small for gestational age. We performed linear regression to estimate difference in birth weight among children of exposed and unexposed mothers. All models were adjusted for maternal age, educational level, ethnicity, and calendar time. We identified 885 exposed pregnancies and 3327 unexposed pregnancies. Relative to unexposed women, exposed women had OR 0.97 (95% CI 0.82, 1.15) for secondary sex ratio, OR 1

Who reads Maternal exposure to airborne polychlorinated biphenyls (PCBs) and risk of adverse birth outcomes?

Author

Ane Bungum Kofoed; Laura Deen; Karin Sørig Hougaard; Kajsa Ugelvig Petersen; Harald William Meyer; Ellen Bøtker Pedersen; Niels Erik Ebbehøj; Berit Lilienthal Heitmann; Jens Peter Bonde; Sandra Søgaard Tøttenborg

Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Medicine (Health Sciences)