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Can I read Placebo controlled phase II clinical trial: Safety and efficacy of combining intranasal insulin & acute exercise on EtoBox?
Placebo controlled phase II clinical trial: Safety and efficacy of combining intranasal insulin & acute exercise by Kathryn L. Gwizdala; David P. Ferguson; Jeffery Kovan; Vera Novak; Matthew B. Pontifex is a Medicine article available to read on EtoBox.
What is Placebo controlled phase II clinical trial: Safety and efficacy of combining intranasal insulin & acute exercise about?
A growing number of investigations are exploring the utility of intranasal insulin as a means of mitigating cognitive decline. However, as a basic tenant of dementia prevention programs is increasing physical activity, it is essential to obtain a preliminary assessment of the safety profile of combining intranasal insulin with physical activity; to ensure that undue risks are not incurred. Utilizing a randomized double-blind placebo-controlled design, a sample of 116 non-diabetic, fasted college-aged adults were randomly assigned to receive a dose of 0-to-120 IU of NovoLog (Insulin Aspart) before being randomized to 20 min of exercise or sitting control condition. The safety of intranasal insulin was assessed by examining the incidence of potential symptoms of hypoglycemia and changes in peripheral blood glucose. The efficacy of a combination therapeutic approach was assessed using behavioral measures of inhibition and sustained attention alongside neuroelectric indices of attentional engagement. The frequency of symptoms reported following administration of intranasal insulin were not observed to interact with exercise so as to make their occurrence any more or less prominent, nor
Who reads Placebo controlled phase II clinical trial: Safety and efficacy of combining intranasal insulin & acute exercise?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Kathryn L. Gwizdala; David P. Ferguson; Jeffery Kovan; Vera Novak; Matthew B. Pontifex
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Medicine (Life Sciences)