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Enhanced Dissolution in Solid Formulations by yitifa4596 is a document available to read on EtoBox.
The article investigates the mechanisms enhancing the dissolution of poorly water-soluble drugs in solid crystalline formulations, focusing on physical mixtures of celecoxib, naproxen, and phenytoin. It identifies that dissolution can be carrier- or drug-controlled, influenced by factors such as drug load, hydrodynamics, and particle size reduction. The study aims to contribute to the understanding of dissolution mechanisms, which is crucial for the development of effective pharmaceutical formulations.
- Author
- yitifa4596
- Language
- EN