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Association between chronic kidney disease and periodontitis. A systematic review and metanalysis by Lapo Serni; Leonardo Caroti; Luigi Barbato; Michele Nieri; Sergio Serni; Calogero Lino Cirami; Francesco Cairo is a Dentistry article available to read on EtoBox.

What is Association between chronic kidney disease and periodontitis. A systematic review and metanalysis about?

## Abstract ## Objectives Aims of this SR were to assess the association of Periodontitis (PD) with Chronic Kidney Disease (CKD) and with different CKD stages. ## Materials and methods MEDLINE, Cochrane Central Register of Trials and EMBASE, up to April 4, 2021 were searched. RCTs, prospective and retrospective cohort studies, case–control studies and cross‐sectional studies were considered. JBI’s Critical Appraisal Tool for risk of bias assessment was used. The risk of PD was calculated using the Mantel–Haenszel odds ratios (MH‐OR); weighted mean difference for clinical attachment level (CAL) and periodontal probing depth (PPD) were also evaluated. ## Results Out of 1949 titles screened, 142 full texts were evaluated and 17 studies were included. CKD was associated to higher risk of PD (MH‐OR = 2.36, [95% C.I. 1.25, 4.44]; p = 0.008), higher mean CAL (WMD = 0.41 mm [95% C.I. 0.22, 0.60]; p < 0.0001) and mean PPD (WMD = 0.25 mm [95% C.I. 0.03, 0.47]; p = 0.02) compared to healthy individuals. Severe CKD (stages 4–5 vs 2–3) resulted at higher risk of PD (MH‐OR = 2.21, [95% C.I. 1.07, 4.54]; p = 0.03). Heterogeneity and risk of bias were high. ## Conclusions An association between PD

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Author

Lapo Serni; Leonardo Caroti; Luigi Barbato; Michele Nieri; Sergio Serni; Calogero Lino Cirami; Francesco Cairo

Publisher

Wiley

Published

2021

Language

EN

Field

Dentistry (Health Sciences)