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Can I read The destinies of human embryos reaching blastocyst stage between Day 4 and Day 7 diverge as early as fertilization on EtoBox?
The destinies of human embryos reaching blastocyst stage between Day 4 and Day 7 diverge as early as fertilization by Giovanni Coticchio; Kenji Ezoe; Cristina Lagalla; Carlotta Zacà; Andrea Borini; Keiichi Kato is a Medicine article available to read on EtoBox.
What is The destinies of human embryos reaching blastocyst stage between Day 4 and Day 7 diverge as early as fertilization about?
## Abstract ## STUDY QUESTION What clinical and laboratory differences emerge from parallel direct comparison of embryos reaching the blastocyst stage between Days 4, 5, 6, and 7 (Days 4–7)? ## SUMMARY ANSWER Increasing times to blastocyst formation are associated with a worse clinical outcome and perturbations in developmental patterns appear as early as the fertilization stage. ## WHAT IS KNOWN ALREADY Previous evidence indicates that later times to blastocyst development are associated with a worse clinical outcome. However, the vast majority of these data concern Day 5 and Day 6 blastocysts, while Day 4 and Day 7 blastocysts remain less thoroughly investigated. In addition, studies comparing in parallel the developmental patterns and trajectories of Day 4–7 blastocysts are lacking. This leaves unanswered the question of when and how differences among such embryos emerge. Acquisition of such knowledge would significantly contribute to understanding the relative impact of intrinsic and extrinsic causes of embryo developmental kinetics and competence. ## STUDY DESIGN, SIZE, DURATION This retrospective study involved time-lapse technology (TLT) monitoring of Day 4 (N = 70), Day 5 (
Who reads The destinies of human embryos reaching blastocyst stage between Day 4 and Day 7 diverge as early as fertilization?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Giovanni Coticchio; Kenji Ezoe; Cristina Lagalla; Carlotta Zacà; Andrea Borini; Keiichi Kato
- Publisher
- Oxford University Press (OUP)
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)