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Targeted siRNA Therapy for TNBC by Rima Luciana Dewi is a document available to read on EtoBox.
What is Targeted siRNA Therapy for TNBC about?
The study investigates the use of EpCAM aptamer-siRNA chimeras (AsiCs) for targeted gene knockdown in epithelial breast cancers, particularly triple negative breast cancer (TNBC). The findings demonstrate that these chimeras effectively inhibit tumor-initiating cells and suppress tumor growth in vivo, indicating their potential as a therapeutic strategy for treating epithelial cancers. The research highlights the selective uptake of AsiCs by EpCAM+ cancer cells, providing a promising approach for RNA interf
- Author
- Rima Luciana Dewi
- Language
- EN