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Myocardial Ischemia and Its Complications by G.A. Fishbein; M.C. Fishbein; L.M. Buja is a book available to read on EtoBox.
What is Myocardial Ischemia and Its Complications about?
Irreversible injury and necrosis of ischemic myocardial extending from subendocardium into subepicardium of LV Coronary plaque erosion or rupture with occlusive thrombosis Acute transmural myocardial infarction Severe coronary atherosclerosis Variable myocardial functional impairment Healed coronary plaque rupture or erosion; inward coronary remodeling; myocardial remodeling Chronic ischemic heart disease; heart failure; ischemic cardiomyopathy 240 7. MYOCARDIAL ISCHEMIA AND ITS COMPLICATIONS Alteration Time Contractile dysfunction Within seconds Initial reduction of adenosine triphosphate (ATP) Within seconds 50% reduction 10 min Ultrastructural changes of reversible injury Within minutes Stretched, wavy cardiac myocytes Within minutes Ultrastructural changes of irreversible injury Within 20 min ATP depletion to less 10% of normal 40 min Microvascular damage After 1 h Histochemical changes including decreased staining with tetrozolium dye 2-3 h Histological changes of necrosis 4-12 h Gross changes of infarction 12-24 h 241 BIOCHEMICAL CHANGES WITH ISCHEMIA AND BIOCHEMICAL MARKERS PHENOMENA ASSOCIATED WITH ISCHEMIC INJURY
- Author
- G.A. Fishbein; M.C. Fishbein; L.M. Buja
- Published
- 2016
- Language
- EN
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