Opening book details…
Can I read Current Role of Surgery for Tuberous Sclerosis Complex‐associated Epilepsy on EtoBox?
Current Role of Surgery for Tuberous Sclerosis Complex‐associated Epilepsy by Nicola Specchio; Giusy Carfi Pavia; Luca de Palma; Alessandro De Benedictis; Chiara Pepi; Marta Conti; Carlo Efisio Marras; Federico Vigevano; Paolo Curatolo is a Medicine article available to read on EtoBox.
What is Current Role of Surgery for Tuberous Sclerosis Complex‐associated Epilepsy about?
## ABSTRACT Tuberous sclerosis complex (TSC) is a rare multisystem, autosomal dominant neurocutaneous syndrome in which epilepsy is the most common of several neurological and psychiatric manifestations. Around two thirds of patients develop drug‐resistant epilepsy for whom surgical resection of epileptogenic foci is indicated when seizures remain inadequately controlled following trial of two antiseizure medications. The challenge with presurgical and surgical approaches with patients with TSC is overcoming the complexity from the number of tubers and the multiplex epileptogenic network forming the epileptogenic zone. Data suggest that seizure freedom is achieved by 55%–60% of patients, but predictive factors for success have remained elusive, which makes for unconfident selection of surgical candidates. This article presents three different cases as illustrations of the potential challenges faced when assessing the suitability of TSC patients for epilepsy surgery.
Who reads Current Role of Surgery for Tuberous Sclerosis Complex‐associated Epilepsy?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Nicola Specchio; Giusy Carfi Pavia; Luca de Palma; Alessandro De Benedictis; Chiara Pepi; Marta Conti; Carlo Efisio Marras; Federico Vigevano; Paolo Curatolo
- Publisher
- Wiley
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)