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This document discusses local control of blood flow through the vascular system. It notes that total blood flow equals cardiac output and is distributed based on metabolic needs through vasoconstriction and vasodilation of arterioles. Blood flow is determined by the pressure gradient across a vessel and its resistance, with resistance largely dependent on arteriole diameter. Arterioles have local control of diameter through paracrines like NO, prostacyclin, endothelin released by the endothelium, responding

Author

Miles Hui

Language

EN