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A Population-based Study of the Use and Outcome of Radical Radiotherapy for Invasive Bladder Cancer by Charles R.R Hayter; Lawrence F Paszat; Patti A Groome; Karleen Schulze; William J Mackillop is a Medicine article available to read on EtoBox.

What is A Population-based Study of the Use and Outcome of Radical Radiotherapy for Invasive Bladder Cancer about?

Purpose: The objective of this study is to describe the use and outcome of radical radiotherapy for bladder cancer in the province of Ontario, Canada, between 1982 and 1994. Methods: Electronic records of invasive bladder cancer (ICD code 188) from the Ontario Cancer Registry were linked to surgical records from all Ontario hospitals and radiotherapy (RT) records from all Ontario cancer centers. We identified cases receiving radical RT by selecting RT records containing "bladder" or "pelvis" anatomic region codes and a radical or curative intent code (or dose > 39.5 Gy if intent missing). We identified cases receiving salvage total cystectomy by selecting total cystectomy procedure codes occurring at any time beyond 4 months from the start of radical RT. We used life table methods to compute the following: the time from diagnosis to radical RT, the time from radical RT to salvage cystectomy, overall and cause-specific survival from radical radiotherapy to death, and overall and cause-specific survival from salvage cystectomy to death. We modeled the factors associated with time to death, time to cystectomy conditional on survival, and time to cystectomy or death, whichever came fir

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Author

Charles R.R Hayter; Lawrence F Paszat; Patti A Groome; Karleen Schulze; William J Mackillop

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

1999

Language

EN

Field

Medicine (Health Sciences)