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Acute graft-versus-host disease (GVHD) is a common complication after allogeneic hematopoietic stem cell transplantation where donor T cells attack minor histocompatibility antigens in the transplant recipient, potentially damaging the skin, gastrointestinal tract, and liver. The risk of acute GVHD can be reduced through prophylaxis regimens using calcineurin inhibitors and methotrexate or anti-thymocyte globulin, though this may also inhibit the graft-versus-leukemia effect from donor T cells fighting the

Author

Aymen Omer

Language

EN