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Prognostic Value of Serum Albumin Level in Critically Ill Patients: Observational Data From Large Intensive Care Unit Databases by Xuting Jin; Jiamei Li; Lu Sun; Jingjing Zhang; Ya Gao; Ruohan Li; Jiajia Ren; Yanli Hou; Dan Su; Jiao Liu; Xiaochuang Wang; Dechang Chen; Gang Wang; Christian J. Wiedermann is a Medicine article available to read on EtoBox.
What is Prognostic Value of Serum Albumin Level in Critically Ill Patients: Observational Data From Large Intensive Care Unit Databases about?
## Background Decreased serum albumin level (SAL) is associated with adverse clinical outcomes. We designed the present study to further assess the prognostic value of SAL in critically ill patients based on data from large intensive care unit (ICU) databases. ## Methods This retrospective cohort study recruited 18,353 patients from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. Restricted cubic splines (RCS) were performed to visualize the association of SAL at admission with ICU and hospital mortalities. The prognostic value of SAL was analyzed using logistic regression models and receiver operating characteristic (ROC) curves in overall patients and subgroups. ## Results Restricted cubic splines revealed rapid increasing risks in ICU and hospital mortalities when SAL declined to below 30 g/l. Patients with SAL <30 g/l (n = 6,069) had higher ICU (13.7% vs. 6.4%, __p__ < 0.001) and hospital (23.9% vs. 10.7%, __p__ < 0.001) mortalities than those with SAL ≥30 g/l. Multivariable logistic regression model revealed that SAL <30 g/l independently correlated with higher risks of both ICU (odds ratio [OR]: 1.20, 95% confidence interval [CI]: 1.07–1.36) and hospit
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- Author
- Xuting Jin; Jiamei Li; Lu Sun; Jingjing Zhang; Ya Gao; Ruohan Li; Jiajia Ren; Yanli Hou; Dan Su; Jiao Liu; Xiaochuang Wang; Dechang Chen; Gang Wang; Christian J. Wiedermann
- Publisher
- Frontiers Media SA
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)